Taiwan DNA Training Workshop


 Two days of presentations at Criminal Investigation Bureau Forensic Science Center (Taipei, Taiwan)

June 6-7, 2012


John M. Butler, Ph.D.

National Institute of Standards and Technology

To view or print slide handouts (6-slides to a page), click on highlighted topics


June 6, 2012

Introduction to NIST & the Applied Genetics Group

SWGDAM Guidelines*

 DNA Mixture Interpretation & Statistical Analysis


June 7, 2012

 Lineage Markers: Y-STRs, X-STRs, and mtDNA

 Capillary Electrophoresis & Troubleshooting Laboratory Problems

 The Future of Forensic DNA Typing


For full-page slides: [Introduction] [SWGDAM Guidelines] [Mixture Interpretation] [Lineage Markers] [CE & Troubleshooting] [Future of Forensic DNA]

*SWGDAM Autosomal STR Interpretation Guidelines (2010). Available at http://www.swgdam.org/Interpretation_Guidelines_January_2010.pdf


Recommended further reading materials:

Butler, J.M. (2012) Advanced Topics in Forensic DNA Typing: Methodology. Elsevier Academic Press: San Diego

Butler, J.M. and Hill, C.R. (2012) Biology and genetics of new autosomal STR loci useful for forensic DNA analysis. Forensic Sci. Rev. 24(1): 15-26

Kline, M.C., Hill, C.R., Almeida, J.L., Butts, E.L.R., Coble, M.D., Butler, J.M. (2011) The latest and greatest NIST PCR-based DNA Profiling Standard: updates and status of Standard Reference Material (SRM) 2391c. Profiles in DNA, Available at http://www.promega.com/resources/articles/profiles-in-dna/2011/the-latest-and-greatest-nist-pcr-based-dna-profiling-standard/


Butler, J.M., Buel, E., Crivellente, F., McCord, B.R. (2004) Forensic DNA typing by capillary electrophoresis: using the ABI Prism 310 and 3100 Genetic Analyzers for STR analysis. Electrophoresis, 25: 1397-1412


Butler, J.M., Coble, M.D., Vallone, P.M. (2007) STRs vs SNPs: thoughts on the future of forensic DNA testing. Forensic Sci. Med. Pathol. 3: 200-205


Vallone, P.M., Hill, C.R., Butler, J.M. (2008) Demonstration of rapid multiplex PCR amplification involving 16 genetic loci. FSI Genetics 3(1): 42-45

Butler, J.M. and Hill, C.R. (2010) Scientific issues with analysis of low amounts of DNA. Profiles in DNA (Promega), 13(1). Available at http://www.promega.com/resources/articles/profiles-in-dna/2010/scientific-issues-with-analysis-of-low-amounts-of-dna/

Buckleton, J.S. and Curran, J.M. (2008) A discussion of the merits of random man not excluded and likelihood ratios. Forensic Sci. Int. Genet. 2: 343-348.


Budowle, B., et al. (2009) Mixture interpretation: defining the relevant features for guidelines for the assessment of mixed DNA profiles in forensic casework. J. Forensic Sci. 54: 810-821.


Clayton, T.M., et al. (1998) Analysis and interpretation of mixed forensic stains using DNA STR profiling. Forensic Sci. Int. 91: 55-70.


Gill, P., et al. (2006) DNA commission of the International Society of Forensic Genetics: Recommendations on the interpretation of mixtures. Forensic Sci. Int. 160: 90-101.


Gill, P., et al. (2008) National recommendations of the technical UK DNA working group on mixture interpretation for the NDNAD and for court going purposes. FSI Genetics 2(1): 76–82.


Schneider, P.M., et al. (2009) The German Stain Commission: recommendations for the interpretation of mixed stains. Int. J. Legal Med. 123: 1-5.

[Return to Home Page]

Revised: 06/04/2012